11/01/2024

Grave violations of human dignity


The Dicastery for the Doctrine of the Faith’s new document 'Dignitas infinita' took five years to complete, and builds on the papal magisterium of the last decade: from war to poverty, from violence against migrants to violence against women, from abortion to surrogate motherhood to euthanasia, from gender theory to digital violence. Three chapters offer the foundations for the fourth, which is dedicated to "some grave violations of human dignity.

That’s the structure of the Dicastery for the Doctrine of the Faith’s new Declaration Dignitas infinita, which commemorates the 75th anniversary of the Universal Declaration of Human Rights and reaffirms "the indispensable nature of the dignity of the human person in Christian anthropology " (Intro.)

The main novelty of the document, which is the fruit of five years' work, is the inclusion of a number of key themes from the recent papal magisterium that accompany the bioethical ones. In the 'non-exhaustive' list that is offered, abortion, euthanasia and surrogate motherhood are listed as violations of human dignity alongside war, poverty and human trafficking.

The new text thus contributes to overcoming the dichotomy that exists between those who focus exclusively on beginning-and-end-of-life issues, while forgetting so many other attacks against human dignity and, conversely, those who focus only on defending the poor and migrants while forgetting that life must be defended from conception to its natural conclusion.

The Declaration then presents the list of "some grave violations of human dignity". This includes "all offences against life itself, such as murder, genocide, abortion, euthanasia, and willful suicide” must be recognized as contrary to human dignity ", but also "all violations of the integrity of the human person, such as mutilation, physical and mental torture, undue psychological pressures "... And, finally, it includes "all offences against human dignity, such as subhuman living conditions, arbitrary imprisonment, deportation, slavery, prostitution, the selling of women and children, degrading working conditions where individuals are treated as mere tools for profit rather than free and responsible persons"... The death penalty is also cited, since it "violates the inalienable dignity of every person, regardless of the circumstances" (34).

More at:  https://www.vaticannews.va/en/vatican-city/news/2024-04/human-dignity-ddf-document-migration-gender-surrogacy-war-theolo.html

 The full text of the Declaration Dignitas infinita on the Holy See website

Source: https://www.vaticannews.va/en/vatican-city/news/2024-04/human-dignity-ddf-document-migration-gender-surrogacy-war-theolo.html

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3/25/2014

A new method of creating versatile stem cells from a relatively simple manipulation of existing cells

A new method of creating versatile stem cells from a relatively simple manipulation of existing cells could further reduce the need for any stem-cell research involving human embryos, according to leading ethicists. Although the process has only been tested in mice, two studies published Jan. 29 in the journal Nature detailed research showing success with a process called stimulus-triggered acquisition of pluripotency, or STAP.  Scientists from Japan's RIKEN research institute and Harvard's Brigham and Women's Hospital in Boston were able to reprogram blood cells from newborn mice by placing them in a low-level acidic bath for 30 minutes. Seven to 9 percent of the cells subjected to such stress returned to a state of pluripotency and were able to grow into other types of cells in the body.

"If this technology proves feasible with human cells, which seems likely, it will offer yet another alternative for obtaining highly flexible stem cells without relying on the destructive use of human embryos," said Fr. Tadeusz Pacholczyk, director of education at the National Catholic Bioethics Center in Philadelphia. "This is clearly a positive direction for scientific research."

The Catholic church opposes any research involving the destruction of human embryos to create stem cells. Richard Doerflinger, associate director of the U.S. bishops' Secretariat for Pro-Life Activities, said if the new method were used to create stem cells so versatile that they could form placenta tissue and make human cloning easier, "then we would have serious moral problems with that." But there is no indication so far that the scientists could or would do so, he added. "You could misuse any powerful technology, but the technique itself is not problematic" in terms of Catholic teaching, Doerflinger said. David Prentice, senior fellow for life sciences at the Family Research Council in Washington, said the new STAP process is yet another indication that "there are all these different ways to create stem cells without ever having to endanger a human being." He said adult stem cells -- drawn from living human beings without harming them, as well as from umbilical cord blood or bone marrow -- "are the only stem cells that have ever proven to help a single patient." More than 60,000 patients around the world are receiving treatments for a variety of diseases from adult stem cells, he added. Another type of adult stem cells, called induced pluripotent stem cells, or iPS cells, is still being used only in animal models, said Prentice, who holds a doctorate in biochemistry and was a founding member of Do No Harm: The Coalition of Americans for Research Ethics. Japanese scientist Shinya Yamanaka received the 2012 Nobel Prize in Physiology or Medicine for his discovery of the iPS technique.

 *More at: http://ncronline.org/news/politics/new-stem-cell-method-offers-another-alternative-embryonic-research

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8/24/2012

US Trial to study cord blood stem cells' effects on autism

Stem cell researchers are launching the first FDA-approved clinical trial to examine whether cord blood stem cells can improve the condition of children with autism. “This is the start of a new age of research in stem cell therapies for chronic diseases such as autism, and a natural step to determine whether patients receive some benefit from an infusion of their own cord blood stem cells,” Dr. Michael Chez, the study’s principal investigator, said Aug. 21. Dr. Chez is the director of Pediatric Neurology with the Sutter Neuroscience Institute in Sacramento, Calif. The institute has joined with the major stem cell bank CBR (Cord Blood Registry) to examine the effect of the stem cell therapy on autistic children. The clinical study will enroll 30 children ages two through seven who are diagnosed with autism and meet other criteria, CBR says. Participants will receive two infusions, one of the child’s own cord blood stem cells and one of a placebo, over 13 months. The trial intends to determine whether the cells help improve patients’ language and behavior. One in 88 children in the U.S. are diagnosed with autism, a developmental disorder that affects social, language and behavioral skills. Chez said there is evidence that some autistic children have dysfunctional immune systems that damage or delay their nervous system development. “Cord blood stem cells may offer ways to modulate or repair the immune systems of these patients which would also improve language and some behavior in children who have no obvious reason to have become autistic,” he said. Umbilical cord blood contains unique stem cells that have been used for more than 20 years to treat some cancers, blood diseases and immune disorders. Dr. Maureen L. Condic, associate professor of Neurobiology and Anatomy at the University of Utah, told CNA she is “intrigued” by the study but “cautious.” “Autism is a very complex and poorly understood condition,” she said Aug. 22. Umbilical cord stem cells are obtained from a patient at birth and are therefore genetically identical to the patient. This means that they will not be rejected by the patient’s immune system. Embryonic stem cells, by contrast, are obtained from human embryos destroyed to produce stem cells. “They are likely to be rejected by the patient's immune system, unless the patient is treated with immune-suppressing drugs,” she added. “Undifferentiated embryonic stem cells produce tumors when injected into patients, and cannot be used for therapies without first manipulating these cells to produce a mature cell type.” Catholic ethics rejects the use of embryonic stem cells because they are derived from destroying a human embryo.

...written by Kevin J. Jones

* See more at http://www.catholicnewsagency.com/news/trial-to-study-cord-blood-stem-cells-effects-on-autism/

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7/17/2012

The Ethical Stems of Good Science by Lozier Institute

A new report on one of the world's largest funders of stem cell research reveals that an emphasis on results has led to a shift in funding towards morally-acceptable work with adult stem cells.In the field of stem cell research, the “predominant progress” is being made by non-controversial adult stem cells, said Chuck Donovan, president of the Charlotte Lozier Institute, which serves as the education and research arm of pro-life Susan B. Anthony List.

Donovan told CNA (Catholic News Agency) on July 16 that an analysis of scientific funding over several years suggests that morally acceptable types of stem cell research offer the greatest promise for a wide variety of effective therapies and treatments. Research on adult stem cells does not require the destruction of a human embryo and therefore does not pose the ethical difficulties associated with embryonic stem cell research. In addition, adult stem cell research has already contributed to advancing therapies for various diseases.

On July 12, the Lozier Institute released a report titled “The Ethical Stems of Good Science,” which examined changes in the funding offered by the California Institute for Regenerative Medicine since 2007. The California institute was created after President George W. Bush announced in 2001 that his administration would become the first to provide federal funding for human embryonic stem cell research, although this funding was limited to stem cell lines that had already been developed.

Dissatisfied with the limits put in place by the president, California established its own Institute for Regenerative Medicine to distribute $3 billion to stem cell research efforts, with a particular emphasis on human embryonic stem cells and other types of research that received limited or no federal funding. One calculation found that the institute was “the largest funder of overall stem cell research in the world” from 2007, when it first began issuing grants, to February 2011. According to the recent Lozier report, the California institute funded more than 100 projects in 2007 involving embryonic research and cloning, while giving virtually no funding to adult or other non-embryonic avenues of stem cell research. In the years that followed, however, the organization’s grants increasingly went to fund projects using non-controversial forms of research.

A new category of grants in 2009 was specifically awarded to projects with “the best chance of resulting in clinical trials,” the report observed. Of these grants, only four went to human embryonic stem cell research, while the remaining 10 went to non-embryonic types of research. This trend has continued every year since 2009, the report found. As grants are awarded “based on their potential to prove therapeutically beneficial,” non-embryonic research receives far more support than embryonic research. The failure of embryonic stem cell research to yield therapeutic results has also led private investors to put their money elsewhere. Last November, the biopharmecuetical company Geron announced that it had ended a widely publicized embryonic stem cell research study due to “capital scarcity.” Donovan said that the shift in funding based on results is logical.

In a statement released with the Lozier report, he explained that “despite the millions of dollars spent on this research, cures brought about by embryonic stem cells have continued to prove elusive, while adult stem cell research applications have exploded.” “As the leading funder of stem cell research, the California Institute for Regenerative Medicine has made grant decisions that show where the industry sees promise,” he noted. “In the past six years, where that promise lies has become increasingly clear: ethical adult stem cell research.” *Source: http://www.catholicnewsagency.com/news/report-shows-adult-stem-cell-research-produces-results-draws-money/

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11/24/2011

Recent Advances in Adult Stem Cell Research

For all interested in recent advances in Adult Stem Cell Research and other alternatives to Embryonic Stem Cell Research see article by DoNoHarm: The Coalition of Americans for Research Ethics, "75 NEW REASONS TO RECONSIDER THE ALLEGED NEED FOR STEM CELL RESEARCH THAT DESTROYS HUMAN EMBRYOS".
See full article at: http://www.stemcellresearch.org/alternatives/75newreasons.pdf

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5/29/2011

"What should be done with all the frozen embryos?"

Good article looking at the stem cell research and in vitro fertilization. "When I give talks on stem cell research or in vitro fertilization, people invariably ask, "What should be done with all the frozen embryos?" It is usually asked with a sense of urgency, even desperation, as they reflect on the fate of the hundreds of thousands of human embryos cryopreserved in liquid nitrogen at fertility clinics. The simple answer is that ethically there is very little we can do with the frozen embryos except to keep them frozen for the foreseeable future. No other morally acceptable options seem to exist.

The question of what to do with the frozen embryos, I sometimes remind my audiences, is not in fact the most pressing question we face. A much more urgent issue is how to stop the relentless manufacturing and freezing of new embryos which is occurring each day, with clockwork-like regularity, in every major city in the United States.

The infertility industry has become an embryo mass-production line with virtually no legal oversight or national regulation. Catering to strong parental desires, it is a multibillion dollar business aptly described as the "wild west of infertility." To start to bring this into check, strong laws and regulations like those found in Germany and Italy are urgently needed. In those countries, no more than three embryos may be produced for each infertility treatment, and all three must be implanted into their mother. Extra embryos may not be produced or frozen; as a result, there are essentially no frozen embryos stored in German and Italian fertility clinics.

For those embryos that do end up abandoned in liquid nitrogen, the question often arises: would it be morally permissible to give them up for "embryo adoption," whereby other couples could implant, gestate and raise them as if they were their own children?

There is ongoing debate among reputable Catholic theologians about this matter, and technically it remains an open question. A recent Vatican document called Dignitas Personae expressed serious moral reservations about the approach, without, however, explicitly condemning it as immoral. But we can easily see reasons why the promotion of embryo adoption would be imprudent. If embryo adoption were to become standard practice in the current, largely unregulated climate of the fertility industry, this could actually stimulate the production of yet more embryos; IVF clinic operators would be able to placate themselves by saying, "We really don't need to worry about producing extra embryos, because there will always be somebody willing to adopt any that are left over." It could offer the clinics an excuse to continue and even expand their current immoral practices.

Some have suggested that a morally acceptable solution to the frozen embryo problem might come through applying the principle that "extraordinary" means do not have to be undertaken to prolong human life. They argue that to sustain an embryo's life in a cryogenic state is to use extraordinary means and this is not required.

In fact, however, the decision to continue cryopreserving an embryo in liquid nitrogen is probably not an instance of using extraordinary means, since the burden and costs involved in taking care of embryonic children in this way are actually minimal. When we have children, we have a duty to clothe, feed, care for, and educate them, all of which costs plenty of money. When our children are frozen, we don’t need to clothe, feed, or educate them; our care for them can only be expressed by paying the bill each month to replenish the liquid nitrogen in their storage tanks. This way of caring for our children is obviously unusual, but it does not seem morally extraordinary in terms of achieving the desired end of safeguarding their physical integrity.

In my opinion, parents have an obligation to care for their children in this way until some other option becomes available in the future (maybe a sophisticated "embryo incubator" or "artificial womb" of some kind), or until there is a reasonable certainty that they have died on their own from decay or "freezer burn," which may occur whenever frozen embryos are stored for extended periods. Perhaps after a few hundred years, all the stored embryos would have died on their own, and they could finally be thawed and given a decent burial. This approach would not involve us in the direct moral agency of ending their lives by withdrawing their life-sustaining liquid nitrogen.

Frozen embryos, clearly, can never be donated to science. Such a decision would amount to handing over not cadavers, but living human beings, for dismemberment at the hands of stem cell researchers. This would always be a radical failure in the parents' duty to protect and care for their offspring.

These considerations indicate the difficulty of answering the question about the disposition of frozen human embryos. We are reminded how sinful choices have consequences, and how the original decision to violate the moral law by doing IVF invariably has grievous repercussions, including the kinds of quandaries considered here, for which no moral resolution is apparent.

Rev. Tadeusz Pacholczyk, Ph.D. earned his PhD from Yale and did post-doctoral work at Harvard. He is a priest of the diocese of Fall River, MA, and serves as the Director of Education at The National Catholic Bioethics Center in Philadelphia.

Source with permission: http://www.ncbcenter.org/NetCommunity/Page.aspx?pid=478

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3/01/2011

New movie: "Lines that Divide: The Great Stem Cell Debate"

"A documentary film on stem cell research: A potential miracle cure for diseases or a form of biological colonialism? The debate still rages over this controversial science. Supporters argue that it is our moral duty to pursue scientific progress that provides healing hope for humanity. Detractors argue that the ends don't justify the means in harvesting some human life to save others. This documentary seeks to educate the public on the scientific basics of stem cell research and the moral issues surrounding it as we enter the 21st century."
1) More at: http://www.linesthatdivide.com/
2) See also following links: http://www.stemcellresearch.org/; http://cbhd.org/.

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