10/08/2020

The development of a vaccine against COVID-19

"Since the start of the Coronavirus outbreak, thousands of people have either fallen ill or lost their lives to this virulent virus. Medical services have also been stretched to their limits. Hopes are being pinned on the development of a vaccine to protect society from the disease".* More and more questions concern about the a potential and the ethical issues surrounding the development and distribution of a vaccine.

*More at: https://www.vaticannews.va/en/church/news/2020-09/uk-bishops-on-ethical-concerns-of-potential-covid-19-vaccine.html

**Further reading: https://www.catholicweekly.com.au/archbishop-fisher-op-lets-not-create-an-ethical-dilemma/ ; http://www.bioethics.org.uk/images/user/covidbriefing2.pdf; https://lozierinstitute.org/an-ethics-assessment-of-covid-19-vaccine-programs/

***COMECE  - https://www.tkkbs.sk/view.php?cisloclanku=20201123034;
https://ec.europa.eu/info/live-work-travel-eu/coronavirus-response/public-health_sk;
http://www.comece.eu/site/en/home;  

****USCCB - https://www.catholicnews.com/use-of-pfizer-moderna-covid-19-vaccines-is-morally-acceptable-say-bishops/

*****KBS: https://www.kbs.sk/obsah/sekcia/h/dokumenty-a-vyhlasenia/p/dokumenty-kbs/c/stanovisko-konferencie-biskupov-slovenska-k-ockovaniu-proti-covid-19, 

https://www.kbs.sk/obsah/sekcia/h/dokumenty-a-vyhlasenia/p/dokumenty-vatikanskych-uradov/c/vakcina-s-rovnym-pristupom-pre-vsetkych

https://www.health.gov.sk/Zdroje?/Sources/psd-subory/Infografiky-psd.zip

Picture: https://theconversation.com/infecting-a-volunteer-with-coronavirus-to-develop-a-vaccine-heres-what-consent-should-look-like-139884

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3/19/2015

Children with three genetic parents

Such an interesting debate in bioethics today. It is the subject of considerable controversy in the field of bioethics... My question is: are we playing God?

What is the mitochondrial treatment performed in the UK? Will have a child patient three parents? Will the law authorizing the adoption of this type of interventions to break the religious and political taboos? What are the risks implied and what new therapies bring?

The legal, ethical and scientific dimensions of the new gene therapy session will discuss Havran dinner with former constitutional judge Professor John Drgonec, a bioethicist and professor Joseph Glasa, physician and biologist and philosopher Professor Peter Sykora.


More at http://www.rtvs.sk/televizia/archiv/7865/61574

See also http://en.wikipedia.org/wiki/Three-parent_baby


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3/25/2014

A new method of creating versatile stem cells from a relatively simple manipulation of existing cells

A new method of creating versatile stem cells from a relatively simple manipulation of existing cells could further reduce the need for any stem-cell research involving human embryos, according to leading ethicists. Although the process has only been tested in mice, two studies published Jan. 29 in the journal Nature detailed research showing success with a process called stimulus-triggered acquisition of pluripotency, or STAP.  Scientists from Japan's RIKEN research institute and Harvard's Brigham and Women's Hospital in Boston were able to reprogram blood cells from newborn mice by placing them in a low-level acidic bath for 30 minutes. Seven to 9 percent of the cells subjected to such stress returned to a state of pluripotency and were able to grow into other types of cells in the body.

"If this technology proves feasible with human cells, which seems likely, it will offer yet another alternative for obtaining highly flexible stem cells without relying on the destructive use of human embryos," said Fr. Tadeusz Pacholczyk, director of education at the National Catholic Bioethics Center in Philadelphia. "This is clearly a positive direction for scientific research."

The Catholic church opposes any research involving the destruction of human embryos to create stem cells. Richard Doerflinger, associate director of the U.S. bishops' Secretariat for Pro-Life Activities, said if the new method were used to create stem cells so versatile that they could form placenta tissue and make human cloning easier, "then we would have serious moral problems with that." But there is no indication so far that the scientists could or would do so, he added. "You could misuse any powerful technology, but the technique itself is not problematic" in terms of Catholic teaching, Doerflinger said. David Prentice, senior fellow for life sciences at the Family Research Council in Washington, said the new STAP process is yet another indication that "there are all these different ways to create stem cells without ever having to endanger a human being." He said adult stem cells -- drawn from living human beings without harming them, as well as from umbilical cord blood or bone marrow -- "are the only stem cells that have ever proven to help a single patient." More than 60,000 patients around the world are receiving treatments for a variety of diseases from adult stem cells, he added. Another type of adult stem cells, called induced pluripotent stem cells, or iPS cells, is still being used only in animal models, said Prentice, who holds a doctorate in biochemistry and was a founding member of Do No Harm: The Coalition of Americans for Research Ethics. Japanese scientist Shinya Yamanaka received the 2012 Nobel Prize in Physiology or Medicine for his discovery of the iPS technique.

 *More at: http://ncronline.org/news/politics/new-stem-cell-method-offers-another-alternative-embryonic-research

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7/04/2011

True Stories: Google Baby, the scary story of the up and coming baby production industry in the age of globalization.

If you still think that the bioethics issues today are "not the big deal ethical issues" then you should see Zippi Brand Frank's documentary 'Google Baby' that gives us a shocking insight into the global business of making babies. What this film shows us is how human beings become tradable commodities in globalized world. In one word: scary!

Google Baby is a journey across three continents telling the story of the up and coming baby production industry in the age of globalization. Doron, an Israeli entrepreneur with a high tech background proposes a new service - Baby production. The baby producer (as he introduces himself) provides customers with a cost effective solution using outsourcing of the surrogacy element to India as way to lower prices. The preferred genetic material is selected by the clients and the rest is left in the hands of the producer: Sperm and eggs are purchased on-line and multiple embryos are produced and frozen. Packed in liquid nitrogen only the embryos that fit the customers preferences are shipped by air to India - where they are implanted into the wombs of local surrogates. The customers arrive only at the end of the nine month pregnancy period to pick up their babies. Today, technology has turned 'making a baby' into an act independent of sex. And globalization is making it affordable.

Source: http://www.hbo.com/documentaries/google-baby/video/trailer.html

***As alternative movie (which I personally recommend)see Eggsploitation made by The Center for Bioethics and Culture Network. Documentary Eggsploitation is a compelling and revealing documentary that gives the viewer an up-close look at the flipside of the infertility industry. See more at http://www.eggsploitation.com/index.htm

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5/29/2011

"What should be done with all the frozen embryos?"

Good article looking at the stem cell research and in vitro fertilization. "When I give talks on stem cell research or in vitro fertilization, people invariably ask, "What should be done with all the frozen embryos?" It is usually asked with a sense of urgency, even desperation, as they reflect on the fate of the hundreds of thousands of human embryos cryopreserved in liquid nitrogen at fertility clinics. The simple answer is that ethically there is very little we can do with the frozen embryos except to keep them frozen for the foreseeable future. No other morally acceptable options seem to exist.

The question of what to do with the frozen embryos, I sometimes remind my audiences, is not in fact the most pressing question we face. A much more urgent issue is how to stop the relentless manufacturing and freezing of new embryos which is occurring each day, with clockwork-like regularity, in every major city in the United States.

The infertility industry has become an embryo mass-production line with virtually no legal oversight or national regulation. Catering to strong parental desires, it is a multibillion dollar business aptly described as the "wild west of infertility." To start to bring this into check, strong laws and regulations like those found in Germany and Italy are urgently needed. In those countries, no more than three embryos may be produced for each infertility treatment, and all three must be implanted into their mother. Extra embryos may not be produced or frozen; as a result, there are essentially no frozen embryos stored in German and Italian fertility clinics.

For those embryos that do end up abandoned in liquid nitrogen, the question often arises: would it be morally permissible to give them up for "embryo adoption," whereby other couples could implant, gestate and raise them as if they were their own children?

There is ongoing debate among reputable Catholic theologians about this matter, and technically it remains an open question. A recent Vatican document called Dignitas Personae expressed serious moral reservations about the approach, without, however, explicitly condemning it as immoral. But we can easily see reasons why the promotion of embryo adoption would be imprudent. If embryo adoption were to become standard practice in the current, largely unregulated climate of the fertility industry, this could actually stimulate the production of yet more embryos; IVF clinic operators would be able to placate themselves by saying, "We really don't need to worry about producing extra embryos, because there will always be somebody willing to adopt any that are left over." It could offer the clinics an excuse to continue and even expand their current immoral practices.

Some have suggested that a morally acceptable solution to the frozen embryo problem might come through applying the principle that "extraordinary" means do not have to be undertaken to prolong human life. They argue that to sustain an embryo's life in a cryogenic state is to use extraordinary means and this is not required.

In fact, however, the decision to continue cryopreserving an embryo in liquid nitrogen is probably not an instance of using extraordinary means, since the burden and costs involved in taking care of embryonic children in this way are actually minimal. When we have children, we have a duty to clothe, feed, care for, and educate them, all of which costs plenty of money. When our children are frozen, we don’t need to clothe, feed, or educate them; our care for them can only be expressed by paying the bill each month to replenish the liquid nitrogen in their storage tanks. This way of caring for our children is obviously unusual, but it does not seem morally extraordinary in terms of achieving the desired end of safeguarding their physical integrity.

In my opinion, parents have an obligation to care for their children in this way until some other option becomes available in the future (maybe a sophisticated "embryo incubator" or "artificial womb" of some kind), or until there is a reasonable certainty that they have died on their own from decay or "freezer burn," which may occur whenever frozen embryos are stored for extended periods. Perhaps after a few hundred years, all the stored embryos would have died on their own, and they could finally be thawed and given a decent burial. This approach would not involve us in the direct moral agency of ending their lives by withdrawing their life-sustaining liquid nitrogen.

Frozen embryos, clearly, can never be donated to science. Such a decision would amount to handing over not cadavers, but living human beings, for dismemberment at the hands of stem cell researchers. This would always be a radical failure in the parents' duty to protect and care for their offspring.

These considerations indicate the difficulty of answering the question about the disposition of frozen human embryos. We are reminded how sinful choices have consequences, and how the original decision to violate the moral law by doing IVF invariably has grievous repercussions, including the kinds of quandaries considered here, for which no moral resolution is apparent.

Rev. Tadeusz Pacholczyk, Ph.D. earned his PhD from Yale and did post-doctoral work at Harvard. He is a priest of the diocese of Fall River, MA, and serves as the Director of Education at The National Catholic Bioethics Center in Philadelphia.

Source with permission: http://www.ncbcenter.org/NetCommunity/Page.aspx?pid=478

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4/08/2011

Ethical Reflections on Embryonic Stem Cell Research by Most Reverend Donald W. Wuerl, Archbishop of Washington

In recent years, much has been written about embryonic stem cell research.I recently found very good article by Most Reverend Donald W. Wuerl, Archbishop of Washington on this bioethical issue, which I want to highly recommend for any bioethicists or general public who want to know more about embryonic stem cell research. Archbishop's letter has been published in the Catholic Standard and entitled as "Ethical Reflections on Embryonic Stem Cell Research".

"Embryos are not the only source of stem cells and arguably not the best source. A number of alternative sources of stem cells offer more realistic hope for cures and treatments of diseases and illnesses. Stem cells from adult tissues have the potential to yield specialized cell types of the tissue from which it originated such as liver (hepatic), brain (neural), or blood (haematopoietic). These are called adult stem cells and scientists today assert that not only are adult stem cells more readily available, they also are more effective."

"Stem cells derived from placental or umbilical cord blood have proven to be remarkably effective, similar to other adult stem cells. Originally it was theorized that stem cells from these various sources would be ineffective because they are limited in their ability to become various types of cells. However, these stem cells from alternative sources have been successfully differentiated into needed tissue and are already healing human illnesses. According to the most recent research, adult stem cells have begun to help patients with over 70 different diseases and injuries."

"Adult stem cell research holds out the promise of a large step forward in the healing process. This research has been described as the most promising advance in medical science in the last decades. The Catholic Church is not opposed to the development of these therapies and remedies for a host of ailments and deficiencies that afflict the body. Stem cell research using stem cells from ethical sources is a continuation of the work that has been done for millennia by physicians and researchers seeking cures for illness and healing for the sick.

What the Church, as the conscience of society, calls for is moral and ethical reflection on the use of human embryos for stem cell research. No scientific, technological, or medical advances should take place divorced from moral and ethical consideration."

"Technology can be a blessing yet, like all science, it requires ethical reflection on its use if it is to be truly at the service of all of us who struggle in the human condition. We all so much long for the cures and therapies that can overcome the physical afflictions of life. At the same time, we need as well to pray for guidance that what we do is what we ought to do. What raises our technological expertise to a truly human level is our capacity to reflect on the ethical and moral dimensions of what we do."

Source: http://www.adw.org/service/stemcells.asp (reposted with permission)
See also: http://www.lifetopics.org/articles.php?subId=26; http://www.youtube.com/watch?v=XrApDP0RD1M&feature=player_embedded

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